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Predictors of reading and spelling skills in German: The role of morphological awareness
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Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia
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In: ISSN: 1359-4184 ; EISSN: 1476-5578 ; Molecular Psychiatry ; https://hal.archives-ouvertes.fr/hal-02976104 ; Molecular Psychiatry, Nature Publishing Group, 2020, ⟨10.1038/s41380-020-00898-x⟩ (2020)
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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In: ISSN: 2158-3188 ; EISSN: 2158-3188 ; Translational Psychiatry ; https://hal.archives-ouvertes.fr/hal-02158502 ; Translational Psychiatry, Nature Pub. Group, 2019, 9, pp.77. ⟨10.1038/s41398-019-0402-0⟩ (2019)
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Reproducibility of Brain Responses: High for Speech Perception, Low for Reading Difficulties
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In: Scientific Reports (2019)
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia ...
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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In: Translational Psychiatry, 9 (1) (2019)
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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School-age outcomes of late-talking toddlers: Long-term effects of an early lexical deficit
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| 9 |
Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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| 10 |
Reproducibility of Brain Responses: High for Speech Perception, Low for Reading Difficulties
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| 11 |
Visual attention span performance in German-speaking children with differential reading and spelling profiles: No evidence of group differences
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In: PLOS One (2018)
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Does the late positive component reflect successful reading acquisition? A longitudinal ERP study
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In: Neuroimage-Clinical (2018)
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Abstract:
Developmental dyslexia is a reading disorder that is associated with deficits in phonological processing, where the exact neural basis for those processing deficits remains unclear. In particular, disagreement exists whether degraded phonological representations or an impaired access to the phonological representations causes these deficits. To investigate this question and to trace changes in neurophysiology during the process of reading acquisition, we designed a longitudinal study with event related potentials (ERPs) in children between kindergarten and second grade. We used an explicit word processing task to elicit the late positive component (LPC), which has been shown to reflect phonological processing. A brain-wide analysis of the LPC with an electrode-wise application of mixed effects models showed significantly attenuated amplitudes in the left temporo-parietal region in dyslexic children. Since these differences were only present in the word and not in the picture (i.e. control) condition, the attenuated amplitudes might reflect impaired access to the phonological representations of words. This was further confirmed by the longitudinal development, which showed a rapid increase in amplitude at the beginning of reading instruction and a decrease with continuing automatization, possibly pointing to a progression from grapheme-phoneme parsing to whole word reading. Our longitudinal study provides the first evidence that it is possible to detect neurophysiological differences in the LPC between children with dyslexia and control children in both preliterate and very early stages of reading acquisition, providing new insights about the neurophysiological development and a potential marker of later reading problems.
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Keyword:
ddc:610; Medizin
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URL: https://epub.ub.uni-muenchen.de/64447/1/64447.pdf
http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-64447-3
https://epub.ub.uni-muenchen.de/64447/
https://doi.org/10.1016/j.nicl.2017.10.014
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| 13 |
White matter alterations and tract lateralization in children with dyslexia and isolated spelling deficits
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| 14 |
Orthographic learning in children with isolated and combined reading and spelling deficits
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| 15 |
Deficits in Letter-Speech Sound Associations but Intact Visual Conflict Processing in Dyslexia: Results from a Novel ERP-Paradigm
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In: Frontiers in Human Neuroscience (2017)
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Visuo-spatial cueing in children with differential reading and spelling profiles
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In: PLOS One (2017)
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Does the late positive component reflect successful reading acquisition? A longitudinal ERP study
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| 18 |
Deficits in Letter-Speech Sound Associations but Intact Visual Conflict Processing in Dyslexia: Results from a Novel ERP-Paradigm
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Visuo-spatial cueing in children with differential reading and spelling profiles
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